Dr DeMott is a graduate of the University of Oregon Medical School (1959). He completed his internship at Madigan General Hospital outside Tacoma, Washington. After service in the U.S. Air Force as a General Medical Officer, he completed the pathology residency program at the University of California San Francisco Medical Center (1967). He was certified in Anatomic and Clinical Pathology by the American Board of Pathology in 1968.

As a practicing pathologist at Providence Medical Center in Kansas City, Kansas from 1968-1994, Dr DeMott gave special attention to the areas of Hematology and Coagulation. He participated in research activities involving separation of white cells from peripheral blood, measurement of zinc levels in peripheral blood leukocytes utilizing atomic absorption spectrophotometry, and separation of neutrophil enzymes by isoelectric focusing. He was an active contributor to the Providence Medical Center (formerly Providence-St Margaret Health Center) School of Medical Technology, is a past president of the Medical Staff of Providence Medical Center, and was chairman or a member of several of the hospital professional committees, including the Cancer Committee. He directed the Cancer Conference for many years.

Dr DeMott is a Fellow of the American Society of Clinical Pathologists and College of American Pathologists, and is a member of the American Association for Clinical Chemistry, American Medical Association, Kansas Society of Pathologists, and Kansas City Society of Pathologists.